By combining experimental screening with computational modeling, we aim to accelerate the discovery of targeted therapies for #neurodegenerative diseases.

#Neuroscience #BrainResearch #ResearchHighlights

Traumatic Brain Injury (#TBI) goes beyond mechanical damage: it disrupts hormones, lipid metabolism, and triggers chronic neuroinflammation.

Discover how our lab models TBI to uncover new therapeutic targets.

Read more in full papers:

https://link.springer.com/article/10.1007/s12035-017-0771-4

https://link.springer.com/article/10.1007/s12035-019-1570-x

In this highlight #2 we uncover how we're decoding hormone-mitochondria interactions.

Read more in our full papers:

Tibolone as Hormonal Therapy and Neuroprotective Agent

In this series, we’ll share a glimpse of research happening at the Barreto Lab. ✨

We believe #mitochondria are more than just energy producers, they are the keys to a healthy brain.

In our lab, we study how these essential organelles are shaped and influenced by sex hormones.

#Neuroscience #BrainResearch #ResearchHighlights

Last week our lab had the pleasure of attending the 13th Steroids and Nervous System Congress in Turin, Italy 🇮🇹

It was a fantastic opportunity to connect with fellow scientists, discuss new ideas, and learn about the latest advances in neurosteroid research and neurobiology.

We were also proud to present our work:

📃 Catarina de Jesus presented a poster titled “β-tibolone modulates astrocytic metabolism and promotes neuroprotection under energy stress.”

🎤 Manuela Faddetta delivered a talk during the Young Investigator Symposium titled “Altered aromatase activity induces mitochondrial dysfunction and metabolic reprogramming in astrocytes.”

A big thank you to the organizers for such an inspiring meeting and to everyone who stopped by to discuss our research. Looking forward to see you in future!

#Neuroscience #SNS26 #Neurosteroids #Research #ScientificConference

🧠 Menopause and brain health: A new frontier